Henzel, J. V., Nabeshima, K., Schvarzstein, M., Turner, B. E., Villeneuve, A. M. & Hillers, K. J. An asymmetric chromosome pair undergoes synaptic adjustment and crossover redistribution during Caenorhabditis elegans meiosis: implications for sex chromosome evolution. Genetics 187, 685-699 (2011). https://www.ncbi.nlm.nih.gov/pubmed/21212235
Nabeshima, K., Mlynarczyk-Evans, S. & Villeneuve, A. M. Chromosome painting reveals asynaptic full alignment of homologs and HIM-8-dependent remodeling of X chromosome territories during Caenorhabditis elegans meiosis. PLoS Genet 7, e1002231 (2011). https://www.ncbi.nlm.nih.gov/pubmed/21876678
Rosu, S., Libuda, D. E. & Villeneuve, A. M. Robust crossover assurance and regulated interhomolog access maintain meiotic crossover number. Science 334, 1286-1289 (2011). https://www.ncbi.nlm.nih.gov/pubmed/22144627
Bessler, J. B., Andersen, E. C. & Villeneuve, A. M. Differential localization and independent acquisition of the H3K9me2 and H3K9me3 chromatin modifications in the Caenorhabditis elegans adult germ line. PLoS Genet 6, e1000830 (2010). https://www.ncbi.nlm.nih.gov/pubmed/20107519
Hayashi, M., Mlynarczyk-Evans, S. & Villeneuve, A. M. The synaptonemal complex shapes the crossover landscape through cooperative assembly, crossover promotion and crossover inhibition during Caenorhabditis elegans meiosis. Genetics 186, 45-58 (2010). https://www.ncbi.nlm.nih.gov/pubmed/20592266
Jaramillo-Lambert, A., Harigaya, Y., Vitt, J., Villeneuve, A. & Engebrecht, J. Meiotic errors activate checkpoints that improve gamete quality without triggering apoptosis in male germ cells. Curr Biol 20, 2078-2089 (2010). https://www.ncbi.nlm.nih.gov/pubmed/20970339
Schvarzstein, M., Wignall, S. M. & Villeneuve, A. M. Coordinating cohesion, co-orientation, and congression during meiosis: lessons from holocentric chromosomes. Genes Dev 24, 219-228 (2010). https://www.ncbi.nlm.nih.gov/pubmed/20123904
Gent, J. I., Schvarzstein, M., Villeneuve, A. M., Gu, S. G., Jantsch, V., Fire, A. Z. & Baudrimont, A. A Caenorhabditis elegans RNA-directed RNA polymerase in sperm development and endogenous RNA interference. Genetics 183, 1297-1314 (2009). https://www.ncbi.nlm.nih.gov/pubmed/19805814
Hillers, K. J. & Villeneuve, A. M. Analysis of meiotic recombination in Caenorhabditis elegans. Methods Mol Biol 557, 77-97 (2009). https://www.ncbi.nlm.nih.gov/pubmed/19799178
Wignall, S. M. & Villeneuve, A. M. Lateral microtubule bundles promote chromosome alignment during acentrosomal oocyte meiosis. Nat Cell Biol 11, 839-844 (2009). https://www.ncbi.nlm.nih.gov/pubmed/19525937
Martinez-Perez, E., Schvarzstein, M., Barroso, C., Lightfoot, J., Dernburg, A. F. & Villeneuve, A. M. Crossovers trigger a remodeling of meiotic chromosome axis composition that is linked to two-step loss of sister chromatid cohesion. Genes Dev 22, 2886-2901 (2008). https://www.ncbi.nlm.nih.gov/pubmed/18923085
Villeneuve, A. M. Ensuring an exit strategy: RTEL1 restricts rogue recombination. Cell 135, 213-215 (2008). https://www.ncbi.nlm.nih.gov/pubmed/18957197
Bessler, J. B., Reddy, K. C., Hayashi, M., Hodgkin, J. & Villeneuve, A. M. A role for Caenorhabditis elegans chromatin-associated protein HIM-17 in the proliferation vs. meiotic entry decision. Genetics 175, 2029-2037 (2007). https://www.ncbi.nlm.nih.gov/pubmed/17237503
Hayashi, M., Chin, G. M. & Villeneuve, A. M. C. elegans germ cells switch between distinct modes of double-strand break repair during meiotic prophase progression. PLoS Genet 3, e191 (2007). https://www.ncbi.nlm.nih.gov/pubmed/17983271
Jaramillo-Lambert, A., Ellefson, M., Villeneuve, A. M. & Engebrecht, J. Differential timing of S phases, X chromosome replication, and meiotic prophase in the C. elegans germ line. Dev Biol 308, 206-221 (2007). https://www.ncbi.nlm.nih.gov/pubmed/17599823
Smolikov, S., Eizinger, A., Hurlburt, A., Rogers, E., Villeneuve, A. M. & Colaiacovo, M. P. Synapsis-defective mutants reveal a correlation between chromosome conformation and the mode of double-strand break repair during Caenorhabditis elegans meiosis. Genetics 176, 2027-2033 (2007). https://www.ncbi.nlm.nih.gov/pubmed/17565963
Smolikov, S., Eizinger, A., Schild-Prufert, K., Hurlburt, A., McDonald, K., Engebrecht, J., Villeneuve, A. M. & Colaiacovo, M. P. SYP-3 restricts synaptonemal complex assembly to bridge paired chromosome axes during meiosis in Caenorhabditis elegans. Genetics 176, 2015-2025 (2007). https://www.ncbi.nlm.nih.gov/pubmed/17565948
Stanfield, G. M. & Villeneuve, A. M. Regulation of sperm activation by SWM-1 is required for reproductive success of C. elegans males. Curr Biol 16, 252-263 (2006). https://www.ncbi.nlm.nih.gov/pubmed/16461278
MacQueen, A. J., Phillips, C. M., Bhalla, N., Weiser, P., Villeneuve, A. M. & Dernburg, A. F. Chromosome sites play dual roles to establish homologous synapsis during meiosis in C. elegans. Cell 123, 1037-1050 (2005). https://www.ncbi.nlm.nih.gov/pubmed/16360034
Martinez-Perez, E. & Villeneuve, A. M. HTP-1-dependent constraints coordinate homolog pairing and synapsis and promote chiasma formation during C. elegans meiosis. Genes Dev 19, 2727-2743 (2005). https://www.ncbi.nlm.nih.gov/pubmed/16291646
Nabeshima, K., Villeneuve, A. M. & Colaiacovo, M. P. Crossing over is coupled to late meiotic prophase bivalent differentiation through asymmetric disassembly of the SC. J Cell Biol 168, 683-689 (2005). https://www.ncbi.nlm.nih.gov/pubmed/15738262
Couteau, F., Nabeshima, K., Villeneuve, A. & Zetka, M. A component of C. elegans meiotic chromosome axes at the interface of homolog alignment, synapsis, nuclear reorganization, and recombination. Curr Biol 14, 585-592 (2004). https://www.ncbi.nlm.nih.gov/pubmed/15062099
Gartner, A., MacQueen, A. J. & Villeneuve, A. M. Methods for analyzing checkpoint responses in Caenorhabditis elegans. Methods Mol Biol 280, 257-274 (2004). https://www.ncbi.nlm.nih.gov/pubmed/15187259
Nabeshima, K., Villeneuve, A. M. & Hillers, K. J. Chromosome-wide regulation of meiotic crossover formation in Caenorhabditis elegans requires properly assembled chromosome axes. Genetics 168, 1275-1292 (2004). https://www.ncbi.nlm.nih.gov/pubmed/15579685
Reddy, K. C. & Villeneuve, A. M. C. elegans HIM-17 links chromatin modification and competence for initiation of meiotic recombination. Cell 118, 439-452 (2004). https://www.ncbi.nlm.nih.gov/pubmed/15315757
Colaiacovo, M. P., MacQueen, A. J., Martinez-Perez, E., McDonald, K., Adamo, A., La Volpe, A. & Villeneuve, A. M. Synaptonemal complex assembly in C. elegans is dispensable for loading strand-exchange proteins but critical for proper completion of recombination. Dev Cell 5, 463-474 (2003). https://www.ncbi.nlm.nih.gov/pubmed/12967565
Hillers, K. J. & Villeneuve, A. M. Chromosome-wide control of meiotic crossing over in C. elegans. Curr Biol 13, 1641-1647 (2003). https://www.ncbi.nlm.nih.gov/pubmed/13678597
Owen, A. B., Stuart, J., Mach, K., Villeneuve, A. M. & Kim, S. A gene recommender algorithm to identify coexpressed genes in C. elegans. Genome Res 13, 1828-1837 (2003). https://www.ncbi.nlm.nih.gov/pubmed/12902378
Colaiacovo, M. P., Stanfield, G. M., Reddy, K. C., Reinke, V., Kim, S. K. & Villeneuve, A. M. A targeted RNAi screen for genes involved in chromosome morphogenesis and nuclear organization in the Caenorhabditis elegans germline. Genetics 162, 113-128 (2002). https://www.ncbi.nlm.nih.gov/pubmed/12242227
Kelly, W. G., Schaner, C. E., Dernburg, A. F., Lee, M. H., Kim, S. K., Villeneuve, A. M. & Reinke, V. X-chromosome silencing in the germline of C. elegans. Development 129, 479-492 (2002). https://www.ncbi.nlm.nih.gov/pubmed/11807039
MacQueen, A. J., Colaiacovo, M. P., McDonald, K. & Villeneuve, A. M. Synapsis-dependent and -independent mechanisms stabilize homolog pairing during meiotic prophase in C. elegans. Genes Dev 16, 2428-2442 (2002). https://www.ncbi.nlm.nih.gov/pubmed/12231631
Chin, G. M. & Villeneuve, A. M. C. elegans mre-11 is required for meiotic recombination and DNA repair but is dispensable for the meiotic G(2) DNA damage checkpoint. Genes Dev 15, 522-534 (2001). https://www.ncbi.nlm.nih.gov/pubmed/11238374
MacQueen, A. J. & Villeneuve, A. M. Nuclear reorganization and homologous chromosome pairing during meiotic prophase require C. elegans chk-2. Genes Dev 15, 1674-1687 (2001). https://www.ncbi.nlm.nih.gov/pubmed/11445542
Villeneuve, A. M. Development. How to stimulate your partner. Science 291, 2099-2101 (2001). https://www.ncbi.nlm.nih.gov/pubmed/11256406
Villeneuve, A. M. & Hillers, K. J. Whence meiosis? Cell 106, 647-650 (2001). https://www.ncbi.nlm.nih.gov/pubmed/11572770
Dernburg, A. F., Zalevsky, J., Colaiacovo, M. P. & Villeneuve, A. M. Transgene-mediated cosuppression in the C. elegans germ line. Genes Dev 14, 1578-1583 (2000). https://www.ncbi.nlm.nih.gov/pubmed/10887151
Kelly, K. O., Dernburg, A. F., Stanfield, G. M. & Villeneuve, A. M. Caenorhabditis elegans msh-5 is required for both normal and radiation-induced meiotic crossing over but not for completion of meiosis. Genetics 156, 617-630 (2000). https://www.ncbi.nlm.nih.gov/pubmed/11014811
Zalevsky, J., MacQueen, A. J., Duffy, J. B., Kemphues, K. J. & Villeneuve, A. M. Crossing over during Caenorhabditis elegans meiosis requires a conserved MutS-based pathway that is partially dispensable in budding yeast. Genetics 153, 1271-1283 (1999). https://www.ncbi.nlm.nih.gov/pubmed/10545458
Dernburg, A. F., McDonald, K., Moulder, G., Barstead, R., Dresser, M. & Villeneuve, A. M. Meiotic recombination in C. elegans initiates by a conserved mechanism and is dispensable for homologous chromosome synapsis. Cell 94, 387-398 (1998). https://www.ncbi.nlm.nih.gov/pubmed/9708740
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Wicky, C., Villeneuve, A. M., Lauper, N., Codourey, L., Tobler, H. & Muller, F. Telomeric repeats (TTAGGC)n are sufficient for chromosome capping function in Caenorhabditis elegans. Proc Natl Acad Sci U S A 93, 8983-8988 (1996). https://www.ncbi.nlm.nih.gov/pubmed/8799140
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Villeneuve, A. M. & Meyer, B. J. The regulatory hierarchy controlling sex determination and dosage compensation in Caenorhabditis elegans. Adv Genet 27, 117-188 (1990). https://www.ncbi.nlm.nih.gov/pubmed/2190446
Villeneuve, A. M. & Meyer, B. J. The role of sdc-1 in the sex determination and dosage compensation decisions in Caenorhabditis elegans. Genetics 124, 91-114 (1990). https://www.ncbi.nlm.nih.gov/pubmed/2307356
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